The Rye Laboratory
Department of Biochemistry and Biophysics
Research
About Research in the Rye Lab
We are broadly interested in understanding how the conformational states of proteins and cellular membranes are monitored and controlled inside a living cell. Using bacteria and yeast as model systems, we employ a variety of methods, including genetics, protein mutagenesis, fluorescence spectroscopy, stopped-flow kinetics and single-molecule fluorescence burst analysis. Projects in the lab cluster into two thematic areas involving (1) protein dynamics and molecular chaperone function and (2) membrane dynamics.